Director, Renal Pathology

  • Board-certified – Anatomic and Clinical Pathology by the American Board of Pathology
  • Fellowship – Surgical Pathology, University of Iowa Hospitals & Clinics, Iowa City, IA
  • Residency –Pathology, University of Iowa Hospitals & Clinics, Iowa City, IA
  • Medical School – University of Iowa College of Medicine, Iowa City, IA
  • Dr. Lager joined the faculty of the Department of Pathology at the University of Iowa and, in 1997, moved to the Mayo Clinic in Rochester, Minnesota. Under her leadership, the Mayo Clinic Renal Biopsy service grew to become one of the largest in the world. Dr. Lager has been active in medical student and resident/fellow education. She has published more than 175 peer-reviewed articles, book chapters, and abstracts and has lectured both nationally and internationally on native renal disease and renal transplant pathology. Dr. Lager is the co-editor of Practical Renal Pathology: A Diagnostic Approach. She also has subspecialty interests in heart transplant pathology, gastrointestinal pathology, and urologic pathology.
  • Joined ProPath in 2009

Peer-Reviewed Articles

  1. Kaila V, Lager DJ, Jain R. A rare tumor presenting as a rectal mass. Gastroenterology. 2018;155(2):273-275.
  2. Sethi S, Haas M, Markowitz GS, D’Agati VD, Rennke HG, Jennette JC, Bajema IM, Alpers CE, Chang A, Cornell LD, Cosio FG, Fogo AB, Glassock RJ, Hariharan S, Kambham N, Lager DJ, Leung N, Mengel M, Nath KA, Roberts IS, Rovin BH, Seshan SV, Smith RJ, Walker PD, Winearls CG, Appel GB, Alexander MP, Cattran DC, Casado CA, Cook HT, De Vriese AS, Radhakrishnan J, Racusen LC, Ronco P, Fervenza FC. Mayo Clinic/Renal Pathology Society consensus report on pathologic classification, diagnosis, and reporting of GN. J Am Soc Nephrol. 2016;27(5):1278-1287.
  3. Nielsen JA, Roberts CA, Lager DJ, Putcha RV, Jain R, Lewin M. Lymphocytic gastritis is not associated with active Helicobacter pylori infection. Helicobacter. 2014;19(5):349-355.
  4. Nielsen JA, Lager DJ, Lewin M, Rendon G, Roberts CA. The optimal number of biopsy fragments to establish a morphologic diagnosis of eosinophilic esophagitis. Am J Gastroenterol. 2014;109(4):515-520.
  5. Nielsen JA, Weber JJ, Lager DJ. Diarrhoea and duodenal disease. Gut. 2014;63(11):1736, 1804.
  6. Nielsen JA, Lager DJ, Lewin M, Weber JJ, Roberts CA. Incidence of diagnostic change in colorectal polyp specimens after deeper sectioning at 2 different laboratories staffed by the same pathologists. Am J Clin Pathol. 2013;140(2):231-237.
  7. Talmon GA, Stanley SM, Lager DJ. Capillary hemangioma of the testis. Int J Surg Pathol. 2011;19(3):398-400.
  8. Halloush R, Lavrovskaya E, Mody DR, Lager DJ, Truong L. Diagnosis and typing of systemic amyloidosis: the role of abdominal fat pad fine needle aspiration biopsy. Cytojournal. 2010;6:24.
  9. Cosio FG, Lager DJ, Lorenz EC, Amer H, Gloor JM, Stegall MD. Significance and implications of capillaritis during acute rejection of kidney allografts. Transplantation. 2010;89(9):1088-1094.
  10. Talmon G, Cornell LD, Lager DJ. Mitochondrial changes in cidofovir therapy for BK virus nephropathy. Transplant Proc. 2010;42(5):1713-1715.
  11. Sethi S, Sukov WR, Zhang Y, Fervenza FC, Lager DJ, Miller DV, Cornell LD, Santhana Krishnan SG, Smith RJH. Dense deposit disease associated with monoclonal gammopathy of undetermined significance. Am J Kidney Dis. 2010;56(5):977-982.
  12. Lorenz EC, Sethi S, Poshusta TL, Ramirez-Alvarado M, Kumar S, Lager DJ, Fervenza FC, Leung N. Renal failure due to combined cast nephropathy, amyloidosis and light-chain deposition disease. Nephrol Dial Transplant. 2010;25(4):1340-1343.
  13. Sukov WR, Ketterling RP, Lager DJ, et al. CCND1 rearrangements and cyclin D1 overexpression in renal oncocytomas: frequency, clinicopathologic features, and utility in differentiation from chromophobe renal cell carcinoma. Hum Pathol. 2009;40(9):1296-1303.
  14. El-Zoghby ZM, Stegall MD, Lager DJ, et al. Identifying specific causes of kidney allograft loss. Am J Transplant. 2009;9(3):527-535.
  15. Czarnecki PG, Lager DJ, Leung N, Dispenzieri A, Cosio FG, Fervenza FC. Long-term outcome of kidney transplantation in patients with fibrillary glomerulonephritis or monoclonal gammopathy with fibrillary deposits. Kidney Int. 2009;75(4):420-427.
  16. Fervenza FC, Croat AJ, Bittar CM, Rosenthal DW, Lager DJ, Leung N, Zendenrust SR, Nath KA. Induction of heme oxygenase-1 and ferritin in the kidney in warm antibody hemolytic anemia. Am J Kidney Dis. 2008;52(5):972-977.
  17. Gloor J, Cosio F, Lager DJ, Stegall MD. The spectrum of antibody-mediated renal allograft injury: implications for treatment. Am J Transplant. 2008;8(7):1367-1373.
  18. Fervenza FC, Torra R, Lager DJ. Fabry disease: an underrecognized cause of proteinuria. Kidney Int. 2008;73(10):1193-1199.
  19. Sukov WR, Lewin M, Sethi S, Rakowski TA, Lager DJ. BK virus-associated nephropathy in a patient with AIDS. Am J Kidney Dis. 2008;51(4):e15-18.
  20. Soares SM, Fervenza FC, Lager DJ, Gertz MA, Cosio FG, Leung N. Bleeding complications after transcutaneous kidney biopsy in patients with systemic amyloidosis: single-center experience in 101 patients. Am J Kidney Dis. 2008;52(6):1079-1083.
  21. Sukov WR, Cheville JC, Lager DJ, Lewin JR, Sebo TJ, Lewin M. Malignant mixed epithelial and stromal tumor of the kidney with rhabdoid features: report of a case including immunohistochemical, molecular genetic studies and comparison to morphologically similar renal tumors. Hum Pathol. 2007;38(9):1432-1437.
  22. Sethi S, Lewin M, Lopez L, Lager DJ. Linear anti-glomerular basement membrane IgG but no glomerular disease: Goodpasture’s syndrome restricted to the lung. Nephrol Dial Transplant. 2007;22(4):1233-1235.
  23. Liang KV, Greene EL, Oei LS, Lewin M, Lager DJ, Sethi S. Nodular glomerulosclerosis: renal lesions in chronic smokers mimic chronic thrombotic microangiopathy and hypertensive lesions. Am J Kidney Dis. 2007;49(4):552-559.
  24. El-Zoghby Z, Lager DJ, Gregoire J, Lewin M, Sethi S. Intra-tubular amyloidosis. Kidney Int. 2007;72(10):1282-1288.
  25. Consugar MB, Kubly VJ, Lager DJ, et al. Molecular diagnostics of Meckel-Gruber syndrome highlights phenotypic differences between MKS1 and MKS3. Hum Genet. 2007;121(5):591-599.
  26. Woollard JR, Punyashtiti R, Richardson S, Masyuk TV, Whelan S, Huang BQ, Lager DJ, van Deursen J, Torres VE, Gattone VH, LaRusso NF, Harris PC, Ward CJ. A mouse model of autosomal recessive polycystic kidney disease with biliary duct and proximal tubule dilatation. Kidney Int. 2007;72(3):328-336.
  27. Fischer EG, Moore MJ, Lager DJ. Fabry disease: a morphologic study of 11 cases. Mod Pathol. 2006;19(10):1295-1301.
  28. Gloor JM, Cosio FG, Rea DJ, Wadei HM, Winters JL, Moore SB, DeGoey SR, Lager DJ, Grande JP, Stegall MD. Histologic findings one year after positive crossmatch or ABO blood group incompatible living donor kidney transplantation. Am J Transplant. 2006;6(8):1841-1847.
  29. Swaminathan S, Lager DJ, Qian X, Stegall MD, Larson TS, Griffin MD. Collapsing and non-collapsing focal segmental glomerulosclerosis in kidney transplants. Nephrol Dial Transplant. 2006;21(9):2607-2614.
  30. Fischer EG, Lager DJ. Anti-glomerular basement membrane glomerulonephritis: a morphologic study of 80 cases. Am J Clin Pathol. 2006;125(3):445-450.
  31. Jevremovic D, Lager DJ, Lewin M. Cystic nephroma (multilocular cyst) and mixed epithelial and stromal tumor of the kidney: a spectrum of the same entity? Ann Diagn Pathol. 2006;10(2):77-82.
  32. Swaminathan S, Leung N, Lager DJ, et al. Changing incidence of glomerular disease in Olmsted County, Minnesota: a 30-year renal biopsy study. Clin J Am Soc Nephrol. 2006;1(3):483-487.
  33. Soares SM, Lager DJ, Leung N, Haugen EN, Fervenza FC. A proliferative glomerulonephritis secondary to a monoclonal IgA. Am J Kidney Dis. 2006;47(2):342-349.
  34. Wadei HM, Rule AD, Lewin M, Mahale AS, Khamash HA, Schwab TR, Gloor JM, Textor SC, Fidler ME, Lager DJ, Larson TS, Stegall MD, Cosio FG, Griffin MD. Kidney transplant function and histological clearance of virus following diagnosis of polyomavirus-associated nephropathy (PVAN). Am J Transplant. 2006;6(5, pt 1):1025-1032.
  35. Gloor JM, Lager DJ, Fidler ME, et al. A comparison of splenectomy versus intensive posttransplant antidonor blood group antibody monitoring without splenectomy in ABO-incompatible kidney transplantation. Transplantation. 2005;80(11):1572-1577.
  36. Pena de la Vega L, Fervenza FC, Lager DJ, Habermann T, Leung N. Acute granulomatous interstitial nephritis secondary to bisphosphonate alendronate sodium. Ren Fail. 2005;27(4):485-489.
  37. Borza DB, Chedid MF, Colon S, Lager DJ, Leung N, Fervenza FC. Recurrent Goodpasture’s disease secondary to a monoclonal IgA1-κ antibody autoreactive with the α1/α2 chains of type IV collagen. Am J Kidney Dis. 2005;45(2):397-406.
  38. Leung N, Lager DJ, Gertz MA, Wilson K, Kanakiriya S, Fervenza FC. Long-term outcome of renal transplantation in light-chain deposition disease. Am J Kidney Dis. 2004;43(1):147-153.
  39. Leung N, Ytterberg SR, Blute ML, Lager DJ, Specks U, Fervenza FC. Wegener’s granulomatosis presenting as multiple bilateral renal masses. Nephrol Dial Transplant. 2004;19(4):984-987.
  40. Dimashkieh HH, Jevremovic D, Blute ML, Lager DJ. Pathologic quiz case: a 56-year-old man with bilateral renal masses. Bilateral renal oncocytosis. Arch Pathol Lab Med. 2004;128(12):e177-8.
  41. Fischer EG, Carney JA, Anderson SR, Klatt EC, Lager DJ. An immunophenotypic comparison of metanephric metaplasia of Bowman capsular epithelium with metanephric adenoma, Wilms tumor, and renal development: a case report and review of the literature. Am J Clin Pathol. 2004;121(6):850-856.
  42. Fidler ME, Gloor JM, Lager DJ, et al. Histologic findings of antibody-mediated rejection in ABO blood-group-incompatible living-donor kidney transplantation. Am J Transplant. 2004;4(1):101-107.
  43. Gloor J, Larson T, Lager DJ, et al. ABO-incompatible kidney transplantation with and without splenectomy using non-A2 blood group donors. Graft. 2004;7(1):18-19.
  44. Shah NS, Kruse SA, Lager DJ, et al. Evaluation of renal parenchymal disease in a rat model with magnetic resonance elastography. Magn Reson Med. 2004;52(1):56-64.
  45. Rosenthal D, Lien YHH, Lager DJ, et al. A novel α-galactosidase A mutant (M42L) identified in a renal variant of Fabry disease. Am J Kidney Dis. 2004;44(5):E85-E89.
  46. Ortiz MC, Manriquez MC, Nath KA, Lager DJ, Romero JC, Juncos LA. Vitamin E prevents renal dysfunction induced by experimental chronic bile duct ligation. Kidney Int. 2003;64(3):950-961.
  47. Buehrig CK, Lager DJ, Stegall MD, et al. Influence of surveillance renal allograft biopsy on diagnosis and prognosis of polyomavirus-associated nephropathy. Kidney Int. 2003;64(2):665-673.
  48. Qian Q, Li A, King BF, Lager DJ, Huston J, Shub C, Davila S, Somlo S, Torres VE. Clinical profile of autosomal dominant polycystic liver disease. Hepatology. 2003;37(1):164-171.
  49. Gloor JM, Lager DJ, Moore SB, et al. ABO-incompatible kidney transplantation using both A2 and non-A2 living donors. Transplantation. 2003;75(7):971-977.
  50. Raife TJ, Lager DJ. Chronic thrombotic microangiopathy associated with antineoplastic therapy with minimal hematological effects. Mayo Clin Proc. 2002;77(4):323-328.
  51. Gloor JM, Cohen AJ, Lager DJ, et al. Subclinical rejection in tacrolimus-treated renal transplant recipients. Transplantation. 2002;73(12):1965-1968.
  52. Martin SA, Mynderse LA, Lager DJ, Cheville JC. Juxtaglomerular cell tumor: a clinicopathologic study of four cases and review of the literature. Am J Clin Pathol. 2001;116(6):854-863.
  53. Muir TE, Cheville JC, Lager DJ. Metanephric adenoma, nephrogenic rests, and Wilms’ tumor: a histologic and immunophenotypic comparison. Am J Surg Pathol. 2001;25(10):1290-1296.
  54. Lager DJ, Qian Q, Bengal RJ, Ishibashi M, Torres VE. The pck rat: a new model that resembles human autosomal dominant polycystic kidney and liver disease. Kidney Int. 2001;59(1):126-136.
  55. Fervenza FC, Kanakiriya S, Kunau RT, Gibney R, Lager DJ. Acute granulomatous interstitial nephritis and colitis in anticonvulsant hypersensitivity syndrome associated with lamotrigine treatment. Am J Kidney Dis. 2000;36(5):1034-40.
  56. Karnes RJ, Gettman MT, Anderson PM, Lager DJ, Blute ML. Primitive neuroectodermal tumor (extraskeletal Ewing’s sarcoma) of the kidney with vena caval tumor thrombus. J Urol. 2000;164(3, pt 1):772.
  57. Lallas TA, Mehaffey PC, Lager DJ, Van Voorhis BJ, Sorosky JI. Malignant cervical schwannoma: an unusual pelvic tumor. Gynecol Oncol. 1999;72(2):238-242.
  58. Peterson JJ, Rayburn HB, Lager DJ, et al. Expression of thrombomodulin and consequences of thrombomodulin deficiency during healing of cutaneous wounds. Am J Pathol. 1999;155(5):1569-1575.
  59. Cheville JC, Sebo TJ, Lager DJ, Bostwick D, Farrow G. Leydig cell tumor of the testis: a clinicopathologic, DNA content, and MIB-1 comparison of nonmetastasizing and metastasizing tumors. Am J Surg Pathol. 1998;22(11):1361-1367.
  60. Raife TJ, Lager DJ, Peterson J, Erger R, Lentz S. Keratinocyte-specific expression of human thrombomodulin in transgenic mice: effects on epidermal differentiation and cutaneous wound healing. J Investig Med. 1998;46(4):127-133.
  61. Buller RE, Skilling JS, Sood AK, Plaxe S, Baergen RN, Lager DJ. Field cancerization: why late “recurrent” ovarian cancer is not recurrent. Am J of Obstet Gynecol. 1998;178:641-649.
  62. Davisson RL, Kim HS, Krege JH, Lager DJ, Smithies O, Sigmund CD. Complementation of reduced survival, hypotension, and renal abnormalities in angiotensinogen-deficient mice by the human renin and human angiotensinogen genes. J Clin Invest. 1997;99(6):1258-1264.
  63. Rasmussen CC, Skilling JS, Sorosky JI, Lager DJ, Buller RE. Stage IIIC ovarian leiomyosarcoma in a premenopausal woman with multiple recurrences: prolonged survival with surgical therapy. Gynecol Oncol. 1997;66(3):519-525.
  64. Skilling J, Sood A, Niemann T, Lager DJ, Buller R. An abundance of p53 null mutations in ovarian carcinoma. Oncogene. 1996;13(1):117-123.
  65. Skilling JS, Powills K, Lager DJ, Anderson B, Sorosky J, Buller RE. p53 allelotypes and enhanced detection of allelic loss in ovarian cancer: lack of correlation with familial and clinical factors. Gynecol Oncol. 1996;61(2):180-188.
  66. Kaplan B, Cooper J, Lager DJ, Abecassis M. Hepatic infarction in a hemodialysis patient with systemic lupus erythematosus. Am J Kidney Dis. 1995;26(5):785-787.
  67. Lager DJ, Huston B, Timmerman T, Bonsib SM. Papillary renal tumors. Morphologic, cytochemical, and genotypic features. Cancer Res. 1995;76(4):669-673.
  68. Lager DJ, Callaghan EJ, Worth SF, Raife TJ, Lentz SR. Cellular localization of thrombomodulin in human epithelium and squamous malignancies. Am J Pathol. 1995;146(4):933-943.
  69. Raife TJ, Lager DJ, Kemp JD, Dick FR. Expression of CD24 (BA-1) predicts monocytic lineage in acute myeloid leukemia. Am J Clin Pathol. 1994;101(3):296-299.
  70. Raife TJ, Lager DJ, Madison KC, et al. Thrombomodulin expression by human keratinocytes: induction of cofactor activity during epidermal differentiation. J Clin Invest. 1994;93(4):1846-1851.
  71. Hochstetler LA, Flanigan MJ, Lager DJ. Transplant-associated thrombotic microangiopathy: the role of IgG administration as initial therapy. Am J Kidney Dis. 1994;23(3):444-450.
  72. Iakoubova O, Wilke W, Burgart L, Slagel DD, Wittchow RJ, Lager DJ, Heller WJ, Robinson RA. Oncogene amplification screening by labeled primer multiplex polymerase chain reaction. Mod Pathol.
    1994;7(7):784-789.
  73. Lager DJ, Slagel D, Palechek P. The expression of epidermal growth factor receptor and transforming growth factor alpha in renal cell carcinoma. Mod Pathol. 1994;7(5):544-548.
  74. Kern JA, Slebos RJC, Top B, Rodenhuis S, Lager DJ, Robinson R, Weiner D, Schwartz DA. C-erbB-2 expression and codon 12 K-ras mutations both predict shortened survival for patients with pulmonary adenocarcinomas. J Clin Invest. 1994;93(2):516-520.
  75. Slagel D, Lager DJ, Dick F. Howell-Jolly body-like inclusions in the neutrophils of patients with acquired immunodeficiency syndrome. Am J Clin Pathol. 1994;101(4):429-431.
  76. Jandik W, Landas S, Bray C, Lager DJ. Scanning electron microscopic distinction of pleural mesotheliomas from adenocarcinomas. Mod Pathol. 1993;6(6):761-764.
  77. Lager DJ, Burgart L, Slagel D. Epstein-Barr virus detection in sequential biopsies from patients with a posttransplant lymphoproliferative disorder. Mod Pathol. 1993;6(1):42-47.
  78. Lager DJ, Slagel D, Burgart L. Detection of Epstein-Barr virus DNA in sequential renal transplant biopsies using the polymerase chain reaction: Report of a patient with a posttransplant lymphoproliferative disorder. Arch Pathol Lab Med. 1993;117(3):308-312.
  79. Lager DJ, Kuper K, Haake G. Subdiaphragmatic extralobar pulmonary sequestration. Arch Pathol Lab Med. 1991;115(5):536-538.
  80. Bonsib S, Bromley C, Lager DJ. Renal oncocytoma: diagnostic utility of cytokeratin-containing globular filamentous bodies. Mod Pathol. 1991;4(1):16-23.
  81. Harris G, Lager DJ. Primary renal lymphoma. J Surg Oncol. 1991;46(4):273-277.
  82. Lager DJ, Landas S. Correlative light and scanning electron microscopy of intestinal giardiasis, cryptosporidiosis and spirochetosis. Ultrastruct Pathol. 1991;15(6):585-591.
  83. Lager DJ, Rosenberg B, Shapiro H, Bernstein J. Lecithin cholesterol acyltransferase (LCAT) deficiency: ultrastructural examination of sequential renal biopsies. Mod Pathol. 1991;4(3):331-335.
  84. Bonsib S, Lager DJ. Chromophobe cell carcinoma: analysis of five cases. Am J Surg Pathol. 1990;14(3):260-267.
  85. Lager DJ, O’Connor J, Robinson R, Brown R, Urdaneta L. Factitious microcalcifications in breast biopsy material: laboratory-induced error by use of tattoo powder for specimen mammography. J Surg Oncol. 1989;40(4):281-282.
  86. Lager DJ, Goeken JA, Kemp JD, Robinson RA. Squamous metaplasia of the prostate. An immunohistochemical study. Am J Clin Pathol. 1988;90(5):597-601.

Book Chapters

  1. Talmon G, Lager DJ. Non-neoplastic renal diseases. In: Cheng L, Bostwick D, eds. Essentials of Anatomic Pathology. 3rd ed. Totowa, NJ: Humana Press; 2011.
  2. Lager DJ. Non-neoplastic renal diseases. In: Cheng L, Bostwick D, eds. Essentials of Anatomic Pathology. 2nd ed. Totowa, NJ: Human Press; 2006.
  3. Zeldenrust S, Lager DJ, Leung N. Light chain deposition disease. In: Gertz M, Greipp P, eds. Hematologic Malignancies: Multiple Myeloma and Related Plasma Cell Disorders. Berlin: Springer; 2004:197-203.
  4. Lager DJ. Non-neoplastic renal diseases. In: Cheng L, Bostwick D, eds. Essentials of Anatomic Pathology. Totowa, NJ: Humana Press; 2002.

Books

  1. Lager DJ, Abrahams N, eds. Practical Renal Pathology: A Diagnostic Approach. Philadelphia, PA: Elsevier Saunders; 2013.

Abstracts

  1. Sorouri M, Lager DJ, Lewin M, Seif FG, Fourment C, Roberts CA, Ritter T. Melanosis coli and tubular adenomas: a microscopic evaluation. American College of Gastroenterology, 2015.
  2. Sorouri M, Seif FG, Fourment C, Lager DJ, Roberts CA, Ritter T, Lewin M. Initial diagnosis of a common hematological malignancy in a screening colonoscopy. American College of Gastroenterology, 2015.
  3. Lager DJ, Nielsen JA, Lewin M, Roberts CA. Esophageal squamous papilloma: no correlation with intraepithelial eosinophils [abstract 758]. Mod Pathol. 2014;27(suppl 2s):186A.
  4. Nielsen JA, Lager DJ, Roberts CA, Lewin M. Fundic gland polyps with dysplasia [abstract 1904757]. Gastroenterology. 2014;146(5)(suppl 1):S-317.
  5. Nielsen JA, Roberts CA, Lager DJ, Putcha R, Jain R, Lewin M. Lymphocytic gastritis is not associated with Helicobacter pylori infection [abstract 1597899]. Gastroenterology. 2013;144(5)(suppl 1):S-327.
  6. Nielsen JA, Lewin M, Roberts CA, Rendon G, Lager DJ. Eosinophilic esophagitis in adults: incidence of self-reported drug allergies [abstract 1597800]. Gastroenterology. 2013;144(5)(suppl 1):S-497.
  7. Nielsen JA, Lager DJ, Lewin M, Roberts CA. The optimal number of biopsy fragments to establish a diagnosis of eosinophilic esophagitis [abstract 696]. Mod Pathol. 2013;26(suppl 2s):168A.
  8. Nielsen JA, Lager DJ, Lewin M, Weber J, Roberts CA. Digging deeper into problematic polyps: incidence of diagnostic change in colorectal polyp specimens after deeper sectioning at two different laboratories [abstract 697]. Mod Pathol. 2013;26(suppl 2s):168A-169A.
  9. Lager DJ, Nielsen JA, Lewin M, Roberts CA. Brunner gland cysts: morphologic and endoscopic features [abstract 675]. Mod Pathol. 2013;26(suppl 2s):162A.
  10. Nielsen JA, Lewin M, Jain R, Putcha R, Lager DJ, Roberts CA. Microscopic colitis: endoscopic and morphologic correlation [abstract 1598954]. Gastroenterology. 2013;144(5)(suppl 1):S-440-S-441.
  11. Halloush RA, Lavroskaya E, Mody DR, Lager DJ, Truong L. Diagnosis and typing of systemic amyloidosis. The role of abdominal fat pad fine needle aspiration biopsy (FPFNA) [abstract 327]. Mod Pathol. 2008;21(suppl 1):73A.
  12. Sukov WR, Carlson AW, Lager DJ, Ketterling RP, Cheville JC. Cyclin D1 overexpression and CCND1 rearrangement in renal oncocytoma: frequency, clinicopathologic features and utility in differentiation from chromophobe renal cell carcinoma [abstract 835]. Mod Pathol. 2008;21(suppl 1):182A-183A.
  13. Jevremovic D, Lewin M, Dogan A, Lager DJ. Membranoproliferative glomerulonephritis (MPGN) associated with chronic lymphoproliferative disorders [abstract 1330]. Mod Pathol. 2008;21(suppl 1):291A-292A.
  14. Sukov WR, Gamez J, Lager DJ, Dogan A, Miller DV. Clinicopathologic & proteomic assessment of dense deposit disease associated with monoclonal gammopathy of undetermined significance [abstract 1345]. Mod Pathol. 2008;21(suppl 1):295A.
  15. Eggert C, Amer H, Lager DJ, Albright R. Novel association of MPGN with Graves’ disease. Am J Kidney Dis. 2007;49(4):A38.
  16. Heilman RL, Lager DJ, Williams JW, Moss A, Reddy KS, Cosio FG. Comparison of kidney allograft histology in recipients on steroid avoidance immunosuppression (SA) compared to standard immunosuppression. Am J Transplant. 2007;7(suppl 2):262.
  17. Czarnecki PG, Griffin MD, Lager DJ, Leung N, Stegall M, Fervenza FC. Long-term outcome of kidney transplantation (KTX) in fibrillary glomerulonephritis. American Society of Nephrology (ASN) Renal Week, San Francisco, CA, 2007.
  18. Eggert C, Lager DJ, Haugen E, Lewin M. Characterization of granulomatous interstitial nephritis at Mayo Clinic over the past decade. Am J Kidney Dis. 2006;47(4):A28.
  19. Sukov W, Cheville J, Lewin J, Lager DJ, Sebo T, Lewin M. Tubulocystic carcinoma of the kidney: a comparison with benign cystic renal tumors. Mod Pathol. 2006;19(suppl 1s):87-88.
  20. Jevremovic D, Lager DJ, Lewin ML. Cystic nephroma and mixed epithelial stromal tumor of the kidney: a spectrum of the same entity? Lab Invest. 2005;85(suppl 1):148A.
  21. Swaminathan S, Lager DJ, Lloyd RV, Larson TS, Stegall MD, Griffin MD. Clinical and histological comparison of collapsing and non-collapsing focal segmental glomerulosclerosis in kidney transplantation. Am J Transplant. 2005;5(suppl s11):195
  22. Gloor JM, DeGoey SR, Winters JL, Lager DJ, Moore SB, Stegall MD. Persistence of donor specific anti-HLA antibodies after complement dependent cytotoxicity crossmatch positive kidney transplantation. Am J Transplant. 2005;5(suppl s11):253.
  23. Berbescu EA, Lager DJ. E-Cadherin pattern of expression differentiates chromophobe renal cell carcinoma from oncocytoma: an immunohistochemical study of 137 renal neoplasms [abstract 590]. Mod Pathol. 2005;18(suppl 1s):129A.
  24. Swaminathan S, Leung N, Lager DJ, Melton LJ, Bergstralh E, Fervenza F. Changing incidence of glomerulonephritis (GN) in Olmsted County, MN: a 30-year biopsy study. ASN/ISN World Congress of Nephrology Meeting, St. Louis, MO, 2004.
  25. Gloor JM, Lager DJ, Griffin MD, Moore SB, Grande JP, Fidler ME, Stegall MD. Different approaches to positive crossmatch kidney transplanataion based on the level of donor specific anti-HLA antibody. ASN/ISN World Congress of Nephrology Meeting, St. Louis, MO, 2004.
  26. Fervenza, FC, Chedid MF, Lager DJ, Leung N, Borza D-B. Recurrent Goodpasture’s disease secondary to a monoclonal IgA-κ antibody autoreactive with the α1/α2 chains of type IV collagen. ASN/ISN World Congress of Nephrology Meeting, St. Louis, MO, 2004.
  27. Ward CJ, Whelan S, Punyashthiti R, Lager DJ, Masyuk T, LaRusso NF, Torres VE, Harris PC. Characterization of a model of hepatic fibrosis and cyst development due to disruption of Pkhd1, the ARPKD gene. ASN/ISN World Congress of Nephrology Meeting, St. Louis, MO, 2004.
  28. Fischer EG, Moore MJ, Lager DJ. Fabry Disease: A morphologic study of 11 cases.  Mod Pathol. 2004;17(suppl 1):286A.
  29. Fischer EG, Lager DJ. Anti-glomerular basement membrane glomerulonephritis: A morphologic study of 80 cases. Mod Pathol. 2004;17(suppl 1):285A.
  30. Lewin M, Lager DJ, Kay PA. Detection of polyoma virus infection in renal allograft biopsies prior to 2000. Mod Pathol. 2004;17(suppl 1):289A.
  31. Mahale AS, Khamash HA, Buehrig CK, Espy M, Schwab TR, Gloor JM, Lager DJ, Fidler ME, Cosio FC, Patel R, Stegall MD, Larson TS, Griffin MD. Limited benefits from Cidofovir therapy combined with reduced immunosuppression in clinically evident BK nephropathy in renal transplants [abstract 153]. Am J Transplant. 2004;4(suppl s8):201.
  32. Gloor JM, DeGoey SR, Griffin MD, Larson TS, Lager DJ, Fidler ME, Moore BS, Stegall MD. Living donor kidney transplantation with and without splenectomy in positive crossmatch patients [abstract 364]. Am J Transplant. 2004;4(suppl s8):258.
  33. Cosio FG, Griffin MD, Grande JP, Lager DJ, Gloor, JM, Velosa JA, Larson TS, Stegall MD. Development of chronic allograft nephropathy (CAN) in “low risk” kidney transplant patients [abstract 436]. Am J Transplant. 2004;4(suppl s8):278.
  34. Gloor JM, Larson TS, Lager DJ, Fidler ME, Moore SB, Winters JL, Stegall MD. ABO incompatible kidney transplantation with and without splenectomy using non-A2 blood group donors [abstract 542]. Am J Transplant. 2004;4(suppl s8):307.
  35. Khamash HA, Mahale A, Buehrig CK, Cosio FC, Lager DJ, Fidler ME, Schwab TR, Gloor JM, Taler SJ, Textor SC, Stegall MD, Larson TS, Griffin MD. Factors associated with development of BK nephropathy among patients receiving kidney transplants at a single center during 2001 [abstract 1562]. Am J Transplant. 2004;4(suppl s8):587.
  36. Khamash HA, Mahale A, Buehrig CK, Cosio FC, Lager DJ, Fidler ME, Schwab TR, Gloor JM, Taler SJ, Textor SC, Stegall MD, Larson TS, Griffin MD. BK nephropathy managed by reduced immunosuppression: progressive loss of graft function is dictated by timing of diagnosis and by extent of the initial fibrotic injury [abstract 1566]. Am J Transplant. 2004;4(suppl s8):588.
  37. Buehrig CK, Hamad A, Kreps MA, Lager DJ, Fidler ME, Gloor JM, Schwab TR, Cosio F, Textor SC, Stegall MD, Larson TS, Griffin MD. Graft outcomes in polyomavirus-associated nephropathy – the influence of surveillance biopsy and conversion to cyclosporine. Am J Transplant. 2003;3(suppl s5):370.
  38. Gloor JM, Moore SB, Fidler ME, Lager DJ, Pineda AA, Larson TS, Griffin MD, Schwab TR, Textor SC, Prieto M, Nyberg SL, Velosa JA, Winters JL, Grande JP, Stegall MD. ABO incompatible kidney transplantation using both A2 and non-A2 living donors. Am J Transplant. 2003;3(suppl s5):200.
  39. Gloor JM, Moore SB, Pineda AA, Lager DJ, Degoey SR, Fidler ME, Larson TS, Griffin MD, Schwab TR, Textor SL, Prieto M, Nyberg SL, Winters JL, Grande JP, Velosa JA, Stegall MD. Living donor kidney transplantation in positive crossmatch patients. Am J Transplant. 2003;3(suppl s5):200.
  40. Hamad A, Buehrig CK, Kreps MA, Lager DJ, Fidler ME, Gloor JM, Schwab TR, Textor SE, Prieto M, Larson TS, Griffin MD, Stegall MD. Frequency of polyomavirus-associated nephropathy in a randomized control trial of tacrolimus versus sirolimus-based immunosuppression. Am J Transplant. 2003;3(suppl s5):189.
  41. Fidler ME, Gloor JM, Lager DJ, Grande JP, Stegall MD. Histologic outcomes in ABO bloodgroup incompatible living donor kidney transplantation. J Am Soc Nephrol. 2002;13:181A.
  42. Buehrig C, Griffin M, Fidler M, Lager DJ. Morphologic features predictive of prognosis in BK virus nephropathy (platform presentation). XXIV International Congress of the International Academy of Pathology Meeting, Amsterdam, The Netherlands, 2002.
  43. Muir TE, Lager DJ. Metanephric adenoma and Wilms tumor: a histologic and immunohistochemical comparison. Mod Pathol. 2001;14(1):118A.
  44. Qian Q, McCarthy JT, Lager DJ. Effects of MMF treatment on idiopathic FSG. NephroAsia Meeting, Singapore, 2001.
  45. Iyer, VK, Lager DJ. Dense Deposit Disease (DDD) in adults (>30 years): significance of associated monoclonal gammopathy of unknown significance (MGUS). J Am Soc Nephrol. 2001;12:108A.
  46. Wang X, Sweeney W, Lager DJ, Harris PC, Frost P, Avner ED, Torres VE. The intraperitoneal administration of EKI-785 has opposing effects on the development of polycystic kidney disease in Han:SPRD and PCK rats.
    J Am Soc Nephrol. 2001;12:546A.
  47. Iyer VK, Lager DJ. Necrotizing and crescentic glomerulonephritis (NCGN) coexisting with membranous nephropathy (MN). J Am Soc Nephrol. 2001;12:108A.
  48. Gloor JM, Lager DJ, Griffin MD, Larson TS, Schwab TR, Velosa JA, Grande JP, Lund WJ, Stegall MD. Subclinical rejection after kidney transplantation: a comparison of tacrolimus and cyclosporine. J Am Soc Nephrol. 2001;12:890A.
  49. Gloor JM, Pineda AA, Moore SB, Schwab TR, Griffin MD, Velosa JA, Larson TS, Grande JP, Lager DJ, Fidler MA, Stegall MD. Expanding the living donor pool: ABO-incompatible kidney transplantation using both A2 and non-A2 blood type donors. J Am Soc Nephrol. 2001;12:890A, 2001.
  50. Erickson LA, Lager DJ. Dense Deposit Disease in adults: association with monoclonal gammopathy of uncertain significance. Mod Pathol. 2000;13(3):174A.
  51. Kanakiriya S, Lager D, Fervenza F. Long term outcome of renal transplantation in light chain deposition disease (LCDD). J Am Soc Nephrol 2000;11:693A.
  52. Qian Q, Lager DJ, Bengal RJ, Ishibashi M, Torres VE. Opposite response to NaHCO3 administration in PCK and Han:SPRD rats. J Am Soc Nephrol. 2000;11:397A.
  53. Lager DJ, Bengal RJ, Ishibashi M, Torres VE. The PCK rat, a new model that closely resembles human autosomal dominant polycystic kidney and liver disease. J Am Soc Nephrol. 1999;10:419A.
  54. Peterson JJ, Rayburn HB, Lager DJ, Kealey GP, Rosenberg RD, Lentz SR. Cutaneous wound healing in thrombomodulin deficient mice. American Society of Hematology Meeting, Miami, FL, 1998.
  55. Raife TJ, Lager DJ, Peterson JJ, Erger RA, Lentz SR. Normal squamous differentiation and wound healing in transgenic mice that express human thrombomodulin in keratinocytes.  XVI Congress of the International Society on Thrombosis and Haemostasis, Florence, Italy, 1997.
  56. Peterson JJ, Lager DJ, Raife TJ, Teredesai M, Lentz SR. Normal epidermal differentiation in transgenic mice expressing human thrombomodulin in keratinocytes. Mod Pathol. 1997;10(1):154A.
  57. Raife TJ, Bonsib SM, Lager DJ. Chronic thromobotic microangiopathy without thrombocytopenia associated with anti-neoplastic therapy. Lab Invest. 1996;74(1):168A.
  58. Cooley ML, Johnson JL, Lager DJ. Thrombomodulin mRNA expression in cervical squamous epithelium using in-situ hybridization. Lab Invest. 1996;74(1):144A.
  59. Cooley ML, Johnson JL, Lager DJ. Thrombomodulin expression in cervical squamous neoplasia correlates with invasion. Lab Invest. 1996;74(1):88A.
  60. Lager DJ, Raife TJ, Lentz SR, Kealey GP. Thrombomodulin expression in healing wounds correlates with keratinocyte stratification. Lab Invest. 1996;74(1):146A.
  61. Raife TJ, Lager DJ, Teredesai M, Lentz SR. Normal epidermal differentiation in transgenic mice expressing human thromobomodulin in keratinocytes. J Investig Med. 1996;44:375A.
  62. Fitzsimmons K, Snider J, Lanza L, Lager DJ. Micro-vessel density in stage II non-small cell carcinoma of the lung is not predictive of survival. Am J Clin Pathol. 1995;103(4):503-504.
  63. Lones M, Hart J, Ferrell L, Lager DJ, Thung SN, Weiss L, Shintaku IP, Geller SA. Post-transplant lymphoproliferative disorder in liver allograft biopsies: immunohistochemistry and in-situ hybridization.
    Mod Pathol. 1995;(1):140A.
  64. Lager DJ, Callaghan EJ, Worth SF, Raife TJ, Lentz SR. Thrombomodulin expression in human squamous epithelium. XV Congress of the International Society on Thrombosis and Hemostasis, Jerusalem, Israel, 1995.
  65. Raife TJ, Lager DJ, Sturm MT, Lentz SR. Thrombomodulin expression and activity in epidermis and epidermal malignancies correlates with squamous differentiation. Mod Pathol 1994;7(1):143A.
  66. Lager DJ, Raife TJ, Lentz SR. Thrombomodulin expression in keratinizing and non-keratinizing stratified squamous epithelium correlates with differentiation. Mod Pathol. 1994;7(1):142A.
  67. Huston BJ, Timmerman TG, Bonsib SM, Lager DJ. Papillary renal tumors: morphologic and chromosomal features. Mod Pathol. 1994;7(1):77A.
  68. Leigh CJ, Wilke W, Mitros FA, Lager DJ. Sensitivity of the polymerase chain reaction (PCR) in the detection of Mycobacterium paratuberculosis in paraffin-embedded tissue. Mod Pathol. 1994;7(1):63A.
  69. Fitzsimmons KM, Niemann TH, Benda JA, Platz CE, Lager DJ. Synaptophysin reactivity in testicular Sertoli and Leydig Cells. Mod Pathol. 1994;7(1):74A.
  70. Lager DJ, Callaghan EJ, Worth SF, Raife TJ, Lentz SR. Cellular localization of thrombomodulin in human epithelium. Clin Res. 1994;42:337A.
  71. Slagel DD, Lager DJ. The expression of transforming growth factor α (TGFα) on tumor vasculature in renal cell carcinoma. Mod Pathol. 1993;6(1):125A.
  72. Slagel DD, Lager DJ. The expression of epidermal growth factor receptor (EGFR) and transforming growth factor α (TGFα) in renal cell carcinoma. Mod Pathol. 1993;6(1):70A.
  73. Hochstetler L, Flanigan M, Lager DJ, Abecassis M. Post-transplant microangiopathy: a frequent complication with substantial morbidity. American Society of Transplant Physicians Meeting, Houston, TX, 1993.
  74. Raife T, Lager DJ, Sturm M, Lentz S. Low constitutive thrombomodulin expression on renal glomerular endothelium may predispose to thrombotic microangiopathy. Am J Clin Pathol. 1993;100(3):324.
  75. Veronezi-Gurwell A, Lager DJ. The expression of estrogen receptor and cathepsin D in infiltrating ductal carcinoma of the breast: correlation with tumor stage and grade. Am J Clin Pathol. 1993;100(3):336.
  76. Raife TJ, Lager DJ, Madison KC, Piette WW, Howard EJ, Sturm MT, Chen Y, Lentz SR. Expression of functional thrombomodulin by human keratinocytes correlates with squamous differentiation. Blood. 1993;82(10)(suppl 1):152A.
  77. Bertolatus JA, Lager DJ. Membranous nephropathy (MN) in the renal allograft: natural history and effect of prednisone (P) therapy.  JASN. 1992;3(3):852.
  78. Lager DJ, Burgart L, Slagel D. Epstein-Barr virus detection in sequential biopsies from patients with post-transplant lymphoproliferative disorder. Mod Pathol. 1992;5(1):102A.
  79. Cheville JC, Lager DJ, Clamon GH. The expression of proliferating cell nuclear antigen (PCNA), epidermal growth factor receptor (EGFR) and cathespin D in non-small cell carcinoma of the lung. Am J Clin Pathol. 1992;98(2):351.
  80. Raife TJ, Lager DJ, Dick FR, Kemp JD. Expression of BA-1 (CD24) Predicts monocytic lineage in acute myeloid leukemia. Am J Clin Pathol. 1992;98(2):368.
  81. Slagel D, Dick F, Lager DJ. Howell-Jolly body-like inclusions in the neutrophils of patients with acquired immune deficiency syndrome. Am J Clin Pathol. 1992;98(2):366-367.
  82. Lager DJ, Landas SK. Correlative light and scanning electron microscopy of intestinal giardiasis, cryptosporidiosis and spirochetosis. Am J Clin Pathol. 1991;95(2):278.
  83. Jandik WR, Landas SK, Bray CK, Lager DJ. Scanning electron microscopic distinction of pleural mesotheliomas from adenocarcinomas. Am J Clin Pathol. 1991;96(3):404-5.
  84. Lager DJ, Sahin A, Lynch C, Robinson RA, Platz, CE. Urethral neoplasms in females. Am J Clin Pathol. 1988;90:500.
  85. Lager DJ, Kemp JD, Robinson RA. Prostatic squamous metaplasia: immunohistochemical characterization with antibodies to prostate-specific antigen and prostatic acid phosphatase. ASCP/CAP Fall Meeting, New Orleans, LA, 1987.

*Mentor to Student/Resident/Fellow

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Donna J. Lager, M.D., FCAP

Director, Renal Pathology

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